<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Krizková, L</style></author><author><style face="normal" font="default" size="100%">Lopes, M H</style></author><author><style face="normal" font="default" size="100%">Polónyi, J</style></author><author><style face="normal" font="default" size="100%">Belicová, a</style></author><author><style face="normal" font="default" size="100%">Dobias, J</style></author><author><style face="normal" font="default" size="100%">Ebringer, L</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antimutagenicity of a suberin extract from Quercus suber cork.</style></title><secondary-title><style face="normal" font="default" size="100%">Mutation research</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acridine Orange</style></keyword><keyword><style  face="normal" font="default" size="100%">Acridine Orange: toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimutagenic Agents</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimutagenic Agents: pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Euglena gracilis</style></keyword><keyword><style  face="normal" font="default" size="100%">Euglena gracilis: drug effects</style></keyword><keyword><style  face="normal" font="default" size="100%">Euglena gracilis: genetics</style></keyword><keyword><style  face="normal" font="default" size="100%">Euglena gracilis: radiation effects</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipids</style></keyword><keyword><style  face="normal" font="default" size="100%">Membrane Lipids</style></keyword><keyword><style  face="normal" font="default" size="100%">Membrane Lipids: pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Mutagenicity Tests</style></keyword><keyword><style  face="normal" font="default" size="100%">Mutagenicity Tests: methods</style></keyword><keyword><style  face="normal" font="default" size="100%">Mutagens</style></keyword><keyword><style  face="normal" font="default" size="100%">Mutagens: toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Ofloxacin</style></keyword><keyword><style  face="normal" font="default" size="100%">Ofloxacin: toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant Extracts</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant Extracts: pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant Shoots</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant Shoots: chemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Spectrophotometry, Ultraviolet</style></keyword><keyword><style  face="normal" font="default" size="100%">Superoxides</style></keyword><keyword><style  face="normal" font="default" size="100%">Superoxides: metabolism</style></keyword><keyword><style  face="normal" font="default" size="100%">Trees</style></keyword><keyword><style  face="normal" font="default" size="100%">Trees: chemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultraviolet Rays</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1999</style></year></dates><volume><style face="normal" font="default" size="100%">446</style></volume><pages><style face="normal" font="default" size="100%">225-30</style></pages><isbn><style face="normal" font="default" size="100%">4217542577</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">The possible protective effect of a suberin extract from Quercus suber cork on acridine orange (AO)-, ofloxacin- and UV radiation-induced mutagenicity (bleaching activity) in Euglena gracilis was examined. To our knowledge, the present results are the first attempt to analyse suberin in relation to mutagenicity of some chemicals. Suberin exhibits a significant dose-dependent protective effect against AO-induced mutagenicity and the concentration of 500 micrograms/ml completely eliminates the Euglena-bleaching activity of AO. The mutagenicity of ofloxacin is also significantly reduced in the presence of suberin (125, 250 and 500 micrograms/ml). However, the moderate protective effect of suberin on UV radiation-induced mutagenicity was observed only at concentrations 500 and 1000 micrograms/ml. Our data shows that suberin extract from Q. suber cork possess antimutagenic properties and can be included in the group of natural antimutagens acting in a desmutagenic manner.</style></abstract><accession-num><style face="normal" font="default" size="100%">10635345</style></accession-num></record></records></xml>